Molecular, Cellular, and Developmental Biology
Undergraduate e-mail: mcdb-ugrad@lifesci.ucsb.edu
Graduate e-mail: mcdb-gradasst@lifesci.ucsb.edu
Web site: http://lifesci.ucsb.edu/MCDB/mcdb_home.html
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Department Chair: Charles E. Samuel
Roymarie Ballester, Ph.D., Albert Einstein College of Medicine, Assistant Professor (eukaryotic cell microbiology)
John A. Carbon, Ph.D., Northwestern University, Professor (biochemistry)
Rolf E. Christoffersen, Ph.D., UC Los Angeles, Associate Professor (plant molecular biology)
Louise Clarke, Ph.D., UC Santa Barbara, Professor (biochemistry and genetics)
Dennis O. Clegg, Ph.D., UC Berkeley, Associate Professor (neurobiology)
James B. Cooper, Ph.D., Washington University, Associate Professor (plant biology)
James Cronshaw, D.Sc., Ph.D., Leeds, Professor Emeritus
John E. Cushing, Ph.D., California Institute of Technology, Professor Emeritus
Diane E. Eardley, Ph.D., UC Berkeley, Associate Professor (cellular immunology)
Ellis Englesberg, Ph.D., UC Berkeley, Professor Emeritus
Profiled Faculty: Stuart C. Feinstein, Ph.D., UC San Francisco, Professor (molecular cell biology and neurobiology)
Ruth R. Finkelstein, Ph.D., Indiana University, Associate Professor (plant biology)
Steven K. Fisher, Ph.D., Purdue University, Professor (neurobiology)
Kathleen Foltz, Ph.D., Purdue University, Assistant Professor (cellular and molecular biology, marine invertebrate development)
Aharon Gibor, Ph.D., Stanford University, Professor Emeritus
David M. Kohl, Ph.D., State University of New York, Lecturer with Security of Employment, (developmental biology)
Philip C. Laris, Ph.D., Princeton University, Professor Emeritus
Nancy L. Lee, Ph.D., University of Pittsburgh, Professor Emerita
G. John Lew, Ph.D., University of Calgary, Assistant Professor (biochemistry, molecular, biology enzymology)
David A. Low, Ph.D., UC Irvine, Professor (microbiology)
Michael J. Mahan, Ph.D., University of Utah, Assistant Professor (microbial pathogenesis)
Daniel Morse, Ph.D., Albert Einstein College of Medicine, Professor (molecular genetics, biochemistry, marine biology, developmental biology)
Henry I. Nakada, Ph.D., Temple University, Professor Emeritus
Eduardo Orias, Ph.D., California Institute of Technology, Professor Emeritus
Stephen J. Poole, Ph.D., UC San Diego, Associate Professor (biochemistry, molecular biology)
Ian K. Ross, Ph.D., McGill University, Professor (cell biology, mycology)
Joel Rothman, Ph.D., University of Oregon, Associate Professor (developmental biology, genetics, biochemistry)
Charles E. Samuel, Ph.D., UC Berkeley, Professor (virology, biochemistry)
Duane Sears, Ph.D., Columbia University, Professor (biochemistry)
William C. Smith, Ph.D., UC Santa Cruz, Assistant Professor (vertebrate developmental biology)
George Taborsky, Ph.D., Yale University, Professor Emeritus
Barry D. Tanowitz, Ph.D., UC Santa Barbara, Lecturer (evolutionary biology)
Edward L. Triplett, Ph.D., Stanford University, Professor Emeritus
Carol A. Vandenberg, Ph.D., UC San Diego, Associate Professor (neurobiology)
Leslie Wilson, Ph.D., Tufts University, Professor
(biochemical pharmacology)
Benjamin E. Reese, Ph.D. (Psychology)
The Department of Molecular, Cellular, and Developmental Biology (MCDB) offers the bachelor of science degree in four departmental majors-biochemistry-molecular biology, cell and developmental biology, microbiology, and pharmacology. In addition, it cooperates with the Department of Ecology, Evolution, and Marine Biology in offering the interdepartmental biological sciences major, with both B.A. and B.S. objectives. The department offers graduate programs leading to the degrees of master of arts and doctor of philosophy, with emphasis in molecular, cellular, and developmental biology. An interdepartmental graduate program is offered in biochemistry and molecular biology, in cooperation with the Department of Chemistry. In addition, a wide range of courses is available to all undergraduates for elective enrollment or for the support of their preparation for degrees in other departments or programs.
Molecular, cellular, and developmental biology majors provide excellent preparation for a wide variety of biology-related careers, including careers in the health sciences, biotechnology, the pharmaceutical industry, agriculture, environmental health and safety, food technology, and forensic science, and for research careers in academic, industry, and government laboratories. Many MCDB students prepare for entry into graduate or professional schools. Students should become familiar with the requirements of programs of interest, and then discuss their undergraduate coursework with their advisor. In general, all of the department's majors are suitable for students preparing for professional schools in medicine, veterinary medicine, dentistry, pharmacy, or nursing, and for graduate programs in biochemistry, cell biology, developmental biology, genetics, immunology, microbiology, molecular biology, neurobiology, pharmacology, or virology. Students with a bachelor's degree who are interested in pursuing a California Teaching Credential should contact the credential advisor in the Graduate School of Education as soon as possible.
The department undergraduate academic advisor is available for counseling on matters such as major requirements, course substitutions, petitions, and career and graduate school information. One faculty member serves each year as graduate advisor, and one faculty member serves as graduate advisor in the interdepartmental program in biochemistry and molecular biology. The graduate program assistant helps graduate students in all matters related to their graduate study. Department publications are available from the undergraduate advisor and the graduate program assistant.
Students with outstanding academic records in biological sciences are encouraged to apply for the senior honors program early in the fall quarter of the senior year. The honors program centers on an independent research project carried out in one of the departmental research groups (MCDB and EEMB 199) and applications are available from the undergraduate advisor.
Students are normally expected to complete all courses required in preparation for the major by the end of their sophomore year, but physics may be delayed until the junior year if necessary. Students with strong high school backgrounds are urged to complete their basic preparation in general chemistry and mathematics during their freshman year. Students with weak mathematics preparation should make up this deficiency by completing intermediate algebra and trigonometry by correspondence through University Extension, preferably during the summer preceding enrollment at UCSB, or by completing Mathematics 15 at UCSB. As the requirements suggest, each major in the department is designed to emphasize a different area in biology.
Upper-division major courses offered on the P/NP-only basis may be taken for major credit to a maximum of 4 units total in any combination for pharmacology and the B.A. in biological sciences or a maximum of 8 units total for the other B.S. majors. All other courses for the major, both preparation and upper-division, must be taken for letter grades.
Students are not admitted directly into the following majors: Biochemistry-Molecular Biology B.S., Biological Sciences B.A. or B.S., Cell and Developmental Biology B.S., Microbiology B.S., and Pharmacology B.S. Instead, they are first admitted to the pre-biology major, and they may advance to full major standing in one of these majors only after fulfilling the pre-major course and grade requirements listed below. Note: Completion of the pre-major does not fully satisfy the preparation for the major requirements for any of the majors. Students should review the full requirement sheet for the major they intend to declare and plan their schedules accordingly. Also note that acceptance into the pre-major does not guarantee admission to full major status.
Students may petition for advancement to full major status in any one of the majors as soon as they have completed the required minimum of eleven courses with a 2.0 or higher grade-point average in sections A, B, and C. At the time of the petition, they must also have a 2.0 or higher grade-point average in all courses attempted toward the major (preparation and upper-division). The P/NP grading option is not allowed for any pre-major courses. All must be completed on a letter-grade basis.
A. The following with a 2.0 or higher grade-point average: MCDB 5A, either EEMB 5B or MCDB 5B, EEMB 5C.
B. The following with a 2.0 or higher grade-point average: MCDB 5AL, either MCDB 5BL or EEMB 5BL, EEMB 5CL
C. Five courses from the following with a 2.0 or higher grade-point average:
Bachelor of Arts-Biological Sciences
UCSB offers both a bachelor of arts (B.A.) and a bachelor of science (B.S.) degree in biological sciences. The B.A. degree is intended to provide flexibility in curriculum planning for students interested in obtaining a degree in biology accompanied by a broader background in the liberal arts. Either degree is acceptable to most graduate and professional schools. Students are encouraged to seek advice from biology faculty and academic advisors regarding which degree option is most appropriate to their career goals.
Students are not admitted directly into the biological sciences major. Instead, they are first admitted to the pre-biology major, and they may advance to full major standing only after fulfilling specified pre-major course and grade requirements. See section entitled "Pre-Biology" for details.
Note: Hyphens indicate that an entire course sequence must be completed as shown to fulfill an area requirement. Note also that a single course, though listed in more than one area, can satisfy only one requirement.
Preparation for the major. MCDB 5A-AL, MCDB 5B-BL or EEMB 5B-BL, and EEMB 5C-CL (transfer students must consult the advisor regarding selected topics MCDB 5AZ, MCDB 5BZ or EEMB 5BZ, and EEMB 5CZ ); Chemistry 1A-AL-B-BL-C-CL or 2A-AL-B-BL-C-CL, 6A-B, and either 107A-B or 130A-B; Mathematics 3A-B or 34A-B, and one of the following: PSTAT 5A or EEMB 30 or Mathematics 3C; Physics 6A-AL-B-BL.
Upper-division major. Thirty-six upper-division units in biological sciences, distributed as follows:
Note: The following courses do not count toward upper-division major credit: EEMB 183, 184, MCDB 182, 183, 184. In addition, no more than 4 units of the following courses combined will apply to the major: EEMB 185-199, MCDB 185-199.
A. Genetics: MCDB 101A (MCDB 101B strongly recommended for students taking 101A) or EEMB 129
B. Physiology: One course or course sequence from MCDB 111, 114, 117; EEMB 141, 143, 154, 155, 156
C. Development and Cell Biology or Biochemistry and Molecular Biology: One course or course sequence from MCDB 103, 108A, 110, 112, 114 (if not used in Area B), 115, 118, 133, 134
D. Ecology or Evolution: One course or course sequence from EEMB 108, 109 (or Geology 148), 113-113L, 120, 131 (or Geology 121), 135, 137 (or Geology 141), 138, 140, 145C
E. Diversity of Form and Structure: One course or course sequence from EEMB 107, 111, 112, 113-113L (if not used in D above), 116, 127, 134, 144; MCDB 131, 137
F. Electives: Additional upper-division courses offered within the Department of Ecology, Evolution, and Marine Biology and the Department of Molecular, Cellular, and Developmental Biology to bring unit total to 36.
Bachelor of Science-Biochemistry-Molecular Biology
This major is designed for students interested in the characteristics of the molecules and the molecular mechanisms involved in living systems. It is especially recommended for those planning graduate work in biochemistry, molecular biology, or microbiology.
Students are not admitted directly into the biochemistry-molecular biology major. Instead, they are first admitted to the pre-biology major, and they may advance to full major standing only after fulfilling specified pre-major course and grade requirements. See section entitled "Pre-Biology" for details.
Note: Hyphens indicate that an entire course sequence must be completed as shown to fulfill an area requirement.
Preparation for the major. MCDB 5A-AL MCDB 5B-BL or EEMB 5B-BL, EEMB 5C-CL (transfer students must consult the advisor regarding selected topics MCDB 5AZ, MCDB or EEMB 5BZ, and EEMB 5CZ); Chemistry 1A-AL-B-BL-C-CL or 2A-AL-B-BL-C-CL, 6A-B-C, either 107A-107B-108 or 130A-B-C; Mathematics 3A-B-C followed by a fourth quarter of mathematics, with Mathematics 5A recommended; Physics 6A-AL-B-BL-C-CL.
Upper-division major. Forty-eight units, distributed as follows:
Note: The following courses do not count toward upper-division major credit: EEMB 183, 184, MCDB 182, 183, 184. In addition, no more than 8 units of the following courses combined will apply to the major: EEMB 185-199, MCDB 185-199.
A. Genetics: MCDB 101A-B
B. Biochemistry: MCDB 108A-B-C
C. Biochemistry laboratory: MCDB 109L
D. Physical Chemistry: Chemistry 113A-B and either Chemistry 112 or 113C
E. Electives: additional courses from the following to bring the total upper-division units to 48: MCDB 103, 108AL, 111, 112, 112L, 114, 115, 117, 118, 119, 126A (or EEMB 126A), 126AL (or EEMB 126AL), 126AS (or EEMB 126AS), 126B, 126BL, 126C, 131, 131L, 132, 132L, 133, 133L, 134, 139, 140L, 167, 186 (or BMB 186), 187, 188, 192, 198, 199; Chemistry 145
Bachelor of Science-Biological Sciences
UCSB offers both a bachelor of arts (B.A.) and a bachelor of science (B.S.) degree in biological sciences. The B.S. degree is intended for those students desiring a more focused and intensive curriculum in biology, including the development of laboratory skills. Either degree is acceptable to most graduate and professional schools. Students are encouraged to seek advice from biology faculty and academic advisors regarding which degree option is most appropriate to their career goals.
Students are not admitted directly into the biological sciences major. Instead, they are first admitted to the pre-biology major, and they may advance to full major standing only after fulfilling specified pre-major course and grade requirements. See section entitled "Pre-Biology" for details.
Note: Hyphens indicate that an entire course sequence must be completed as shown to fulfill an area requirement.
Preparation for the major. MCDB 5A-AL, MCDB 5B-BL or EEMB 5B-BL, and EEMB 5C-CL (transfer students must consult the advisor regarding selected topics MCDB 5AZ, MCDB 5BZ or EEMB 5BZ, and EEMB 5CZ ); Chemistry 1A-AL-B-BL-C-CL or 2A-AL-B-BL-C-CL, 6A-B and either 107A-B or 130A-B; Mathematics 3A-B or 34A-B, and one of the following: PSTAT 5A or EEMB 30 or Mathematics 3C; Physics 6A-AL-B-BL-C-CL.
Upper-division major. Forty-eight units, distributed as follows:
Note: The following courses do not count toward upper-division major credit: EEMB 183, 184, MCDB 182, 183, 184. In addition, no more than 8 units of the following courses combined will apply to the major: EEMB 185-199, MCDB 185-199.
A. Genetics: MCDB 101A and MCDB 101B (MCDB concentration) or EEMB 129 and EEMB 130 (EEMB concentration)
B. One course or course sequence from each of the following. Note: Courses listed in more than one section can be applied to only one section.
Bachelor of Science-Cell and Developmental Biology
Modern cell and developmental biology brings together a diverse group of disciplines and technologies linked by the common goals of understanding the nature and behavior of cells and how these cells work together to assemble an organism. Whereas some cell and developmental biologists may concentrate on the role that one particular molecule plays within cells, others study the way that many different molecules assemble into structures such as chromosomes or the nucleus, while others may examine how groups of cells interact to form systems of greater complexity, ultimately leading to the progression of a fertilized egg through the many stages of development to form an adult organism. The range of instruments and methods employed by cell and developmental biologists is equally diverse, including recombinant DNA technology, biochemistry, cell culture, genetics, light and electron microscopy, and many others.
The course requirements for the major in cell and developmental biology reflect the diversity within the field. Upper-division coursework includes work in genetics, cell biology, developmental biology (students may choose from among animal, plant, and neuronal development), biochemistry, and additional electives, including extensive laboratory experience. The major is designed to prepare students for graduate training in a wide range of molecular, cellular and developmental biology disciplines; medical, dental, nursing, optometry, and other health-related professions; and employment in the public or private sector (such as biotechnology) research communities.
Students are not admitted directly into the cell and developmental biology major. Instead, they are first admitted to the pre-biology major, and they may advance to full major standing only after fulfilling the pre-major course and grade requirements. See section entitled "Pre-Biology" for details.
Note: Hyphens indicate that an entire course sequence must be completed as shown to fulfill an area requirement.
Preparation for the major. MCDB 5A-AL, MCDB 5B-BL or EEMB 5B-BL, EEMB 5C-CL (transfer students must consult the advisor regarding selected topics from MCDB 5AZ, MCDB or EEMB 5BZ, and EEMB 5CZ); Chemistry 1A-AL-B-BL-C-CL or 2A-AL-B-BL-C-CL, 6A-B and either 107A-B-108 or 130A-B-C; Mathematics 3A-B or 34A-B, and one of the following: PSTAT 5A or EEMB 30 or Mathematics 3C; Physics 6A-AL-B-BL-C-CL.
Upper-division major. Forty-eight units, distributed as follows:
Note: The following courses do not count toward upper-division major credit: EEMB 183, 184, MCDB 182, 183, 184. In addition, no more than 8 units of the following courses combined will apply to the major: EEMB 185-199, MCDB 185-199.
A. Genetics: MCDB 101A-B
B. Biochemistry: MCDB 108A-B-C
C. Cell Biology: MCDB 103
D. Developmental Biology: Two courses from: MCDB 112, 115, 118,
E-1. One course from: MCDB 103L, 112L, 120L
E-2. One course or course sequence from: MCDB 101L, 109L, 126A-AL-AS (or EEMB 126A-AL-AS), 126B-BL, 132-132L, 133-133L, 140L
F. Electives: Additional upper-division courses offered within the Department of Molecular, Cellular, and Developmental Biology and the Department of Ecology, Evolution, and Marine Biology to bring unit total to 48 units.
Bachelor of Science-Microbiology
Microbiology has been and continues to be at the forefront in contributing to human welfare and to our understanding of the basic mechanisms of life processes. Three concentrations in microbiology are available.
General microbiology will provide the student with a broad knowledge of both procaryotic and eucaryotic microorganisms. Such a background will form the basis for understanding the relationships between the various groups of microorganisms and their environment and the relationship of those microorganisms to human welfare. This program will stress the contribution of microbiology to our understanding of basic life processes, and will provide a background for careers in food, industrial, marine, and pharmacological microbiology, and for graduate work in microbiology.
Biomedical sciences, in addition to providing a basic training in microbiology, will also provide a specialized background for students whose careers lie in the fields of medical technology and for those who wish to pursue graduate work in medical or clinical microbiology.
Genetic engineering, in addition to providing a basic training in microbiology, will provide specialized training in the methodology of recombinant DNA research. This area of research is paving the way for a fundamental understanding of the nature of the eucaryotic gene and its regulation. It is also ushering in a revolution in the pharmaceutical industry in the production of hormones and other biologically useful agents.
Students are not admitted directly into the microbiology major. Instead, they are first admitted to the pre-biology major, and they may advance to full major standing only after fulfilling specified pre-major course and grade requirements. See section entitled "Pre-Biology" for details.
Note: Hyphens indicate that an entire course sequence must be completed as shown to fulfill an area requirement.
Preparation for the major. MCDB 5A-AL, MCDB 5B-BL or EEMB 5B-BL, EEMB 5C-CL (transfer students must consult the advisor regarding selected topics from MCDB 5AZ, MCDB or EEMB 5BZ, and EEMB 5CZ); Chemistry 1A-AL-B-BL-C-CL or 2A-AL-B-BL-C-CL; Chemistry 6A-6B and either 107A-B-108 or 130A-B-C; Mathematics 3A-B or 34A-B and one of the following: PSTAT 5A or EEMB 30 or Mathematics 3C; Physics 6A-AL-B-BL-C-CL.
Upper-division major. Forty-nine upper-division units required, distributed as follows: MCDB 101A-B, 108A-B-C, 131-131L, 132-132L, 133 (133L strongly recommended), 134, 135, plus 4 units from the following: MCDB 108AL, 133L, 137, 139, 140L, EEMB 111, 134, 144. Students are encouraged to select their elective courses from within one of the tracks below.
A. General Microbiology: EEMB 134, 144, and MCDB 108AL, 133L, 137
B. Bio-Medical Sciences: MCDB 108AL, 133L, 139 and EEMB 111
C. Genetic Engineering: MCDB 108AL, 133L, 140L
Bachelor of Science-Pharmacology
The emphasis in this major is on pharmacology as a basic science, rather than on the therapeutic principles of pharmacology. The curriculum content is designed to prepare students for careers in pharmaceutical research-and-development laboratories; the program also provides a strong background for graduate study in pharmacology.
Students are not admitted directly into the pharmacology major. Instead, they are first admitted to the pre-biology major, and they may advance to full major standing only after fulfilling the pre-major course and grade requirements. See section entitled "Pre-Biology" for details.
Note: Hyphens indicate that an entire course sequence must be completed as shown to fulfill an area requirement.
Preparation for the major. MCDB 5A-AL, MCDB 5B-BL or EEMB 5B-BL, EEMB 5C-CL (transfer students must consult the advisor regarding selected topics from MCDB 5AZ, MCDB or EEMB 5BZ, EEMB 5CZ); Chemistry 1A-AL-B-BL-C-CL or 2A-AL-B-BL-C-CL; Chemistry 6A-B and either 107A-B-108 or 130A-B-C; Mathematics 3A-B or 34A-B and one of the following: PSTAT 5A or EEMB 30 or Mathematics 3C or Psychology 5; Physics 6A-AL-6B-BL-6C-CL.
Upper-division major. Fifty upper-division units, distributed as follows:
Note: No more than 16 total units may be taken outside the Department of Molecular, Cellular, and Developmental Biology. Courses that are cross-listed between MCDB and other departments do not count towards the 16-unit maximum. Instructor approval required prior to enrollment in psychology courses.
A. Pharmacology: EEMB 126A-AL (or MCDB 126A-AL), EEMB 126AS, MCDB 126B-BL-C
B. Biochemistry: MCDB 108A-B-C or Chemistry 142A-B-C
C. Genetics: MCDB 101A-B
D. Additional courses from the following to bring the total upper-division units in the major to 50. MCDB 103, 108AL, 109L, 111, 112, 112L, 114, 115, 131, 131L, 132, 132L, 133, 133L, 134, 135, 139, 140L, 186, 187, 198, 199; EEMB 111, 126MM, 144, 154, 155; Chemistry 162, 181; Psychology 115, 133A, 133B, 137. Note: A maximum of 4 units of the following courses allowed: EEMB 185-199, MCDB 185-199, BMB 195-199.
Students are encouraged to select their elective courses from within one of these tracks:
Graduate-level research in the Department of Molecular, Cellular, and Developmental Biology (MCDB) spans a wide range of topics including biochemistry, cell biology, cell physiology, developmental biology, gene regulation, genetics, immunology, microbiology, molecular marine biology, neurobiology, pharmacology, plant molecular biology, plant physiology, and virology. The department offers graduate studies leading to the master of arts and doctor of philosophy degrees in molecular, cellular, and developmental biology. Candidates for graduate degrees must meet university degree requirements found in the chapter, "Graduate Education at UCSB," as well as departmental requirements.
Admission
In addition to fulfilling university requirements for admission to graduate status described in the chapter "Graduate Education at UCSB," the applicant will normally hold a bachelor's degree in biology or a biological specialty area (such as biochemistry, cell and developmental biology, microbiology, molecular biology, physiology, or genetics). Undergraduate class work should include one year each of general biology, general chemistry, organic chemistry, calculus, and physics. Upper-division courses should include biochemistry, genetics, and additional specialized electives relevant to preparation for graduate work in molecular, cellular, and developmental biology.
Applicants with strong undergraduate records who lack some of the preparatory class work listed above may be admitted with the condition that they complete the necessary coursework early in their graduate careers.
The general test (verbal, quantitative, and analytical) of the Graduate Record Examination (GRE) is required of all applicants. One of the three following subject tests is also required: biochemistry, cell and molecular biology; biology; or chemistry.
Applicants whose native language is not English must receive a score of at least 610 on the Test of English as a Foreign Language (TOEFL), taken within two years of their application to UCSB. Students who have earned a bachelor's or master's degree from a U.S. college or university are exempt from this requirement.
Applications for admission must be received by January 1. Further details on admission to the MCDB graduate programs can be seen on the web site at http://lifesci.ucsb.edu/MCDB/gradprog/gradprog.htm.
Requirements for the M.A.
A candidate for the master's degree must fulfill, in addition to general university requirements, the minimum lower- and upper-division requirements or their equivalents for the major in their field of emphasis. Students admitted with deficiencies must remedy them early in their graduate studies.
Two plans are available. Under Plan 1 (thesis), students are required to successfully complete (1) a research thesis; (2) the MCDB 218A-B-C core series (with a grade of B or better in each course); and (3) a minimum of 30 units of coursework. The units may be taken in graduate or upper-division courses in the department; at least 20 units will normally be in the 200 and 500 series, excluding 597 and 598. No unit credit is allowed for the thesis.
Under Plan 2 (examination), students are required to successfully complete: (1) the MCDB 218A-B-C core series (with a grade of B or better for each course); (2) at least two additional MCDB graduate lecture courses; and (3) a total of at least 36 units of MCDB graduate lecture courses and literature courses. Up to 6 units of MCDB 596 research coursework may count toward this total. Certain graduate lecture courses in the Interdepartmental BMB Program may be used as well (BMB 242, 245, 246, 254, 256A, 256B). Upper-division undergraduate lecture courses may also count toward the degree with the approval of the graduate advisor. Units in the following courses may not be counted towards the degree: MCDB 260, 262, 263, 269, 290, 595.
Participation in the departmental research seminar program is expected of all MCDB graduate students.
Students admitted to the M.A.-only program may petition to transfer into a Ph.D. program only on the basis of compelling justification. Petitions will be acted upon by the appropriate admissions committee, and admission to the Ph.D. program will be based on the same criteria applied to applications from all other entering Ph.D. students. Successful transfer from M.A. to Ph.D. program will also depend on satisfactory progress in all graduate courses and written support by at least three faculty members. If the petition is approved, the student should consult with the appropriate graduate advisor regarding Ph.D. program requirements.
Students admitted to M.A./Ph.D. programs may petition the graduate committee to drop the M.A. requirements after a minimum of two quarters of graduate study. Petitions will be acted upon by the graduate advisor following review by the graduate committee, and action on such petitions will be contingent upon satisfactory progress in the graduate core course (MCDB 218A-B-C) and the written support of at least two faculty members. As with all other Ph.D. students, continuation in the Ph.D. program is also contingent upon the successful completion of two qualifying examinations, each consisting of a written research proposition followed by an oral defense of the proposition.
Requirements for the Ph.D.
Candidates for the degree of doctor of philosophy must normally have the bachelor's degree in biological sciences, with a preparation deemed equivalent to that required for the bachelor's degree from UCSB. Students who are admitted to graduate standing with deficiencies in preparation will be required to take appropriate undergraduate courses.
Students who entered the department with a specialization in biochemistry-molecular biology or physiology-cell biology prior to or during the 1992-93 year should consult the graduate advisor regarding the requirements of their respective programs. The following unified requirements, in addition to the dissertation, apply to all students entering the Ph.D. program after the 1992-93 academic year: (1) students must pass two qualifying examinations, each consisting of a written research proposition followed by an oral defense of the proposition. These examinations will normally be taken at the beginning of the second and third years of graduate study, respectively. The first proposition will deal with an area of molecular and cell biology distinct from the student's anticipated dissertation research, while the second proposition will be focused on the student's dissertation project; (2) the student must pass, with a grade of B or better, the MCDB 218A-B-C graduate core courses and one additional graduate level, non-seminar course; and (3) students are expected to participate fully in the seminar programs of the department (with the advice of the graduate advisor).
During each quarter of the student's graduate study, enrollment is also required in MCDB 260 (Research Seminar), and in MCDB 262 and 263 (Literature in Molecular Biology). In addition, enrollment in two graduate literature seminars per year in the 260 or 595 series is required until formal admission to candidacy for the Ph.D.
All doctoral candidates must qualify for and hold a teaching assistantship for the equivalent of two quarters as part of the preparation for the Ph.D. degree; take two qualifying examinations administered by the department; complete a doctoral dissertation under the general supervision of a committee; and defend their dissertation in a final oral examination. With the approval of the candidate's doctoral committee, a scheduled departmental seminar may be substituted in lieu of the final oral examination.
Interdepartmental Graduate Program in Biochemistry and Molecular Biology
For details see catalog entry under Biochemistry and Molecular Biology.
Molecular, Cellular, and Developmental Biology Courses
4FS. Freshman Seminar
(1) Staff
Not open for credit to students who have completed
Biology 4FS. Same course as EEMB 4FS.
Selected topics of special interest designed to display
the broad diversity of the biological sciences. This course is strongly
recommended for freshmen and/or prospective majors within the biological
sciences. (F)
5A. Introductory Biology I
(4) Christoffersen, Wilson
Prerequisites: Chemistry 1A-B-C. Not open for credit
to students who have completed Biology 4A or MCDB 4A. Lecture, 4 hours.
Introduction to biochemistry, cell biology and development,
and genetics. (F)
5AL. Introductory Biology Laboratory I
(1) Staff
Prerequisites: Chemistry 1A-B-C. MCDB 5A (can be taken
concurrently). Not open for credit to students who have completed Biology
4A or MCDB 4A. Laboratory, 3 hours.
Laboratory investigations illustrate basic principles
of biochemistry, molecular and cell biology, development, and genetics.
(F)
5AZ. Selected Topics from MCDB 5A
(1-3) Staff
Prerequisite: consent of department. Not open for
credit to students who have completed Biology 4AZ or MCDB 4AZ. Lecture,
1-4 hours.
Designed for transfer students who have completed part
of MCDB 5A through transfer work. Topics will be selected by the department,
as appropriate, to fulfill the introductory biology requirement at UCSB.
(F)
5B. Introductory Biology II
(4) Fisher, Finkelstein
Prerequisite: MCDB 5A. Not open for credit to students
who have completed Biology 4B or EEMB 4B or MCDB 4B. Same course as EEMB
5B. Lecture, 4 hours.
Introduction to animal and plant physiology, population
and community ecology, and
evolution. (W)
5BL. Introductory Biology Laboratory II
(1) Staff
Prerequisites: MCDB 5A, concurrent enrollment in MCDB
5B or EEMB 5B. Not open for credit to students who have completed Biology
4B or EEMB 4B or MCDB 4B. Same course as EEMB 5BL. Laboratory, 3 hours.
Laboratory investigations illustrate basic principles
of animal and plant physiology, ecology, and evolution. (W)
5BZ. Selected Topics from MCDB 5B
(1-3) Staff
Prerequisite: consent of department. Not open for
credit to students who have completed Biology 4BZ or EEMB 4BZ or MCDB 4BZ.
Same course as EEMB 5BZ. Lecture, 1-4 hours.
Designed for transfer students who have completed part
of EEMB 5B or MCDB 5B through transfer work. Topics will be selected by
the department, as appropriate, to fulfill the introductory biology requirement
at UCSB. (W)
5DK. Freshman Seminar-Let's Talk
(1) Kohl
Prerequisite: freshmen only. Not open for credit to
students who have completed Interdisciplinary Studies 94S. Seminar, 1 hour.
Informal discussions on topics in biomedical ethics.
Topics will include recombinant DNA technology, AIDS, euthanasia, abortion,
doctor-patient relationships. (F,W,S)
20. Concepts of Biology
(4) Tanowitz
Not open for credit toward graduation to students
who have completed Natural Science 1C. Not open for credit to students
who have completed Biology 20, or 4A-B-C; or MCDB 4A, EEMB 4B or MCDB 4B,
and EEMB 4C; or MCDB 5A-AL, EEMB 5B-BL or MCDB 5B-BL, and EEMB 5C-CL. Same
course as EEMB 20. Lecture, 3 hours; discussion, 1 hour.
Unifying principles of biology; cell structure, functions,
and energy relations; cybernetics, natural selection, evolution; reproduction
and the principles of genetics and development; nature and growth of populations.
(S)
21. The Immune System and AIDS
(4) Eardley
Not open for credit to students who have completed
Biology 21. Lecture, 3 hours; discussion, 1 hour.
The basic properties of the immune system; the basic
biology of AIDS and AIDS virus infection; and the biology of other sexually
transmitted
diseases. (W,S)
23. Biology of Cancer
(3) Kohl
An introduction to developments regarding the etiology
and treatment of various cancers. Lectures compare normal cells and tissues
with those which have become malignant. Discussion of causes, treatment,
and prevention of specific cancers. (W)
24. Genetics and Human Disease
(3) Kohl
Lecture, 3 hours
Introduction to genetics with emphasis on humans. Topics
focus on human diseases with strong evidence for genetic components. Diseases
covered include cancer, cystic fibrosis, Huntington's, muscular dystrophy,
and others. (S)
25. Human Anatomy
(4) Tanowitz
Recommended: EEMB 20 or MCDB 20 or other course in
biology. Same course as EEMB 25. Not open for credit to students who have
completed Zoology 25. Lecture, 3 hours; discussion, 1 hour.
Emphasis on fundamental structural and functional approaches
of organ systems based on the human organism. Discussion of modern biomedical
advances, techniques, and current topics in relation to their respective
systems. (F,W)
25L. Laboratory in Human Anatomy
(4) Tanowitz
Prerequisite: MCDB 25 or EEMB 25 (may be taken concurrently).
Same course as EEMB 25L. Not open for credit to students who have completed
Zoology 25L. Laboratory, 8 hours; discussion, 1 hour.
Emphasis on fundamental structural and functional approaches
of organ systems based on the human organism. Discussion of modern biomedical
advances, techniques, and current topics in relation to their respective
systems. (W,S)
28. The Biology of Aging
(4) Ross
Not open for credit to students who have completed
Biology 28, or 4A-B; or MCDB 4A, MCDB 4B or EEMB 4B; or MCDB 5A-AL, EEMB
5B-BL or MCDB 5B-BL. Lecture, 3 hours; discussion, 1 hour.
Concepts of cell, human, and population aging emphasizing
biological research in aging problems and the social, ethical, and political
consequences of aging studies. (W)
90A. Honors Forum in Molecular, Cellular, Developmental
Biology
(2) Kohl
Prerequisites: honors standing in College of Letters
and Science and consent of instructor. Seminar, 2 hours.
Seminar for selected students in Molecular, Cellular
and Developmental Biology. Students will be introduced to research opportunities
in the department. Focus will center on the use of the science library
and the Internet as tools to produce a basic research paper. (F)
90B. Honors Forum in Molecular, Cellular, Developmental
Biology
(2) Kohl
Prerequisites: honors standing in College of Letters
and Science and consent of instructor. Seminar, 2 hours.
Continuation of MCDB 90A. Students are introduced to
various faculty in the department and begin reading and reviewing some
of the original literature in the field. Students are expected to critically
analyze basic research papers. (W)
90C. Honors Forum in Molecular, Cellular, Developmental
Biology
(2) Kohl
Prerequisites: honors standing in College of Letters
and Science and consent of instructor. Seminar, 2 hours.
Continuation of MCDB 90B. Students meet with selected
faculty in a defined area of research interest, attend various research
seminars and laboratory meetings, and begin involving themselves with a
research group. (S)
91A. Biological Aspects of Health and Disease I
(2) Kohl
Not open for credit to students who have completed
Biology 91A. Seminar, 2 hours; discussion, 2 hours.
Focus on the treatment and prevention of common upper
respiratory infections and coronary heart disease. Health professionals
teach blood pressure measurement and throat culture skills. Students required
to demonstrate patient educator skills. (F,W,S)
91B. Biological Aspects of Health and Disease II
(2) Kohl
Prerequisites: MCDB 91A or Biology 91A and consent
of instructor. Not open for credit to students who have completed Biology
91B. Seminar, 1 hour; field, 5 hours.
Seminars emphasize the analysis and delivery of health
information, elaborating upon topics initiated in MCDB 91A. Field placement
is within Student Health Services as a patient educator. Focusing upon
upper respiratory infections, students will be required to take throat
cultures. (F,W,S)
91C. Biological Aspects of Health and Disease III
(2) Kohl
Prerequisites: MCDB 91A and consent of instructor.
Not open for credit to students who have completed Biology 91C. Lecture,
1 hour; field, 5 hours.
Seminars emphasize the analysis and delivery of health
information, elaborating upon topics initiated in MCDB 91A. Field placement
is within Student Health Services as a patient educator. Focusing upon
prevention of cardiovascular disease, students will take blood pressure
measurements. (F,W,S)
92A. Special Topics in Biology
(1) Feinstein
Prerequisites: concurrent enrollment in MCDB 5A-AL,
participation in Biology Achievement Program, and consent of instructor.
Not open for credit to students who have completed Biology 92A. Discussion,
1 hour.
An enrichment course for students considering careers
in biomedical sciences or other biological sciences disciplines. (F)
92B. Special Topics in Biology
(1) Feinstein
Prerequistes: concurrent enrollment in MCDB 5B-BL
or EEMB 5B-BL, participation in Biology Achievement Program, and consent
of instructor. Not open for credit to students who have completed Biology
92B. Discussion, 1 hour.
An enrichment course for students considering careers
in the biomedical sciences or other biological sciences disciplines. (W)
98. Readings in Biology
(1-3) Staff
Prerequisites: (1) minimum 3.0 cumulative grade-point
average; (2) consent of instructor and department. Students are limited
to 5 units per quarter and 30 units total in all 98/99/198/199/199RA courses
combined. Students are limited to 6 units of Biology 98 and MCDB 98 combined.
Tutorial, 1 hour.
Special readings on selected topics in biology. Individual
conferences one hour every week. Designed to broaden the outlook and experience
of advanced lower-division students. Hours and credit by arrangement with
any member of the staff.
99. Introduction to Research
(1-3) Staff
Prerequisites: (1) minimum 3.0 cumulative grade-point
average; (2) consent of instructor and department. Students are limited
to 5 units per quarter and 30 units total in all 98/99/198/199/199RA courses
combined. Students are limited to 6 units of Biology 99 and MCDB 99 combined.
Tutorial, 3-9 hours.
Laboratory experience for advanced lower-division students.
Hours and credit by arrangement with any member of the staff.
Completion of all listed prerequisites with a grade of C or better (unless otherwise noted) or consent of instructor is required for all upper-division courses.
101A. Molecular Genetics I: Prokaryotes
(4) Morse, Low
Prerequisites: MCDB 5A-AL, EEMB 5B-BL or MCDB 5B-BL,
and EEMB 5C-CL, and Chemistry 1A-B-C. Not open for credit to students who
have completed Biology 130A. Lecture, 3 hours; discussion, 1 hour.
From the double helix and genetic code to the latest
breakthroughs. Structure, function, evolution and manipulation of DNA,
RNA. Replication, expression, recombination, complementation and their
regulation in prokaryotes (bacteria, plasmids, viruses). Recombinant DNA
technology in medicine, research, agriculture, and industry. (F,W,SS)
101B. Molecular Genetics II: Eukaryotes
(4) Poole, Christoffersen
Prerequisite: MCDB 5A-AL, EEMB 5B-BL or MCDB 5B-BL,
and MCDB 101A. Not open for credit to students who have completed Biology
130B. Lecture, 3 hours; discussion, 1 hour.
Mendelian and molecular genetics. Replication, recombination,
transmission and expression of DNA in eukaryotic organisms from yeast to
man. Uses of traditional genetics and modern molecular techniques, including
molecular genetic approaches to the study of human disease. (W,S,SS)
101L. Molecular Genetics Laboratory
(3) Christoffersen, Finkelstein
Prerequisite: MCDB 101A-B. Completion of all listed
prerequistes with a grade of B or better, or consent of instructor. Not
open for credit to students who have completed Biology 130L. Laboratory,
8 hours.
Laboratory study of eukaryotic molecular genetics using
model genetic systems such as humans, Drosophila, yeast, and Aribidopsis.
Techniques include DNA extraction, DNA fingerprint analysis using PCR,
gel electrophoresis, and computer analysis of genetic mapping data. (W)
103. Cell Biology
(4) Staff
Prerequisites: MCDB 5A-AL, EEMB 5B-BL or MCDB 5B-BL
or equivalents. Not open for credit to students who have completed Biology
137. Lecture, 3 hours; discussion, 1 hour.
An introduction to the structure and function of cell
organelles: membranes, nucleus, mitochondria, chloroplasts, endoplasmic
reticulum, golgi apparatus, lysosomes, microbodies, microtubules, cilia,
centrioles, and microfilaments. (W)
103L. Laboratory in Molecular Cell Biology
(4) Staff
Prerequisites: MCDB 5A-AL, EEMB 5B-BL or MCDB 5B-BL,
and MCDB 103 (may be taken concurrently). Not open for credit to students
who have completed Biology 137L. Laboratory, 9 hours; discussion, 1 hour.
Laboratory techniques of modern cell biology; molecular
dissection of cell structure and
function. (S)
108A. General Biochemistry
(4) Sears
Prerequisites: MCDB 5A-AL, EEMB 5B-BL or MCDB 5B-BL,
Chemistry 1A-B-C, and one year of organic chemistry. Chemistry 108 strongly
recommended. Not open for credit to students who have completed Biology
108A. Lecture, 3 hours; discussion, 1 hour.
Chemistry of proteins; enzymic catalysis. (F)
108AH. General Biochemistry-Honors
(1) Sears
Prerequisites: concurrent enrollment in MCDB 108A
or 108AL and consent of instructor.
Honors component of MCDB 108A designed to permit an in-depth
consideration of selected aspects of the structure/function relationships
of proteins and nucleic acids. (F)
108AL. Biochemistry Computer Laboratory
(2) Sears
Prerequisite: MCDB 108A (may be taken concurrently).
Mathematics 3A-B or 34A-B strongly recommended.
Computer laboratory analysis of biochemical structures
and the dynamics of their interactions with other molecules. (F)
108B. General Biochemistry
(4) Lew
Prerequisite: MCDB 108A. Not open for credit to students
who have completed Biology 108B. Lecture, 3 hours; discussion, 1 hour.
Cellular biochemistry; metabolic pathways responsible
for the generation of cellular energy and the biosynthesis of, and localization
of, cellular components; biochemistry of transmembrane signaling and cancer;
metabolic regulatory mechanisms. (W)
108C. General Biochemistry
(4) Clarke
Prerequisites: three quarters of organic chemistry
and MCDB 108A-B. Not open for credit to students who have completed Biology
108C. Lecture, 3 hours; discussion, 1 hour.
Chemistry and metabolism of nucleic acids; nucleotide
metabolism; biochemical aspects of chromosome structure, replication, and
function. (S)
109L. Laboratory in Biochemistry
(4) Poole
Prerequisites: MCDB 108A. Not open for credit to students
who have completed Biology 109L. Laboratory, 6 hours; tutorial, 6 hours.
Laboratory techniques in biochemistry. Emphasis on techniques
used in modern protein and nucleic acid biochemical research. Includes
aspects of the use of computer analysis and recombinant DNA techniques
in modern biochemistry. (F,S)
110. Principles of Biochemistry
(4) Rothman, Taborsky
Prerequisites: Chemistry 1A-B-C, 107A-B, or consent
of the instructor. Not for specialized majors in molecular, cellular, and
developmental biology, physiology, or students who have completed Biology
108A-B-C or MCDB 108A-B-C. Not open for credit to students who have completed
Biology 118. Lecture, 3 hours; discussion, 1 hour.
An introduction to molecular structures and mechanisms
of living systems. (W,S)
111. Introduction to Physiology
(4) Smith
Prerequisite: MCDB 5A-AL or equivalent. Not open for
credit to students who have completed Biology 100. Lecture, 3 hours; discussion,
1 hour.
Structural and functional characteristics of membranes
in relation to cellular communication. Study of the electrical properties
of the hormonal visceral motor pathways of the central nervous system and
some neural and hormonal visceral motor pathways. (F)
112. Developmental Biology
(3) Foltz
Prerequisites: MCDB 5A-AL, EEMB 5B-BL or MCDB 5B-BL,
and EEMB 5C-CL, and MCDB 101A. MCDB 101B recommended (may be taken concurrently).
Not open for credit to students who have completed Zoology 100. Lecture,
3 hours.
Modern aspects of animal development. Molecular and cellular
mechanisms of embryogenesis. (W)
112L. Laboratory in Developmental Biology
(2) Foltz
Prerequisites: MCDB 5A-AL, EEMB 5B-BL or MCDB 5B-BL,
and EEMB 5C-CL, and MCDB 101A and concurrent enrollment in MCDB 112. Not
open for credit to students who have completed Zoology 100L. Laboratory,
3 hours; discussion, 1 hour.
Modern laboratory techniques in developmental biology.
Experimental approaches to development using several animal model systems.
(W)
114. Neurobiology I
(4) Fisher, Johnson
Prerequisites: MCDB 5A-AL, EEMB 5B-BL or MCDB 5B-BL,
and EEMB 5C-CL or equivalents. Not open for credit to students who have
completed Biology 105. Lecture, 3 hours; discussion, 1 hour.
Properties of the nervous system ranging from single
cells to the whole organism, using examples from vertebrates and invertebrates
studied in terms of morphology, physiology, and behavior. (F)
115. Developmental Neurobiology: A Molecular and Cellular
Perspective
(4) Staff
Prerequisites: MCDB 5A-AL, EEMB 5B-BL or MCDB 5B-BL,
and EEMB 5C-CL; MCDB 101A. MCDB 112 recommended. Not open for credit to
students who have completed Biology 106. Lecture, 3 hours; discussion,
1 hour.
The course begins with fertilization and moves through
sequential stages in the development of the nervous system, including cell
migration and differentiation, axon outgrowth and pathfinding, programmed
cell death, synaptogenesis, learning, memory, neurodegenerative conditions
and current strategies for neuronal regeneration. (S)
117. Plant Physiology
(4) Cooper
Prerequisites: MCDB 5A-AL, EEMB 5B-BL or MCDB 5B-BL
or equivalents; Chemistry 107A-B and 108, or 130A-B-C. Not open for credit
to students who have completed Biology 110 or Botany 120. Lecture, 3 hours;
discussion, 1 hour.
Exploration of the function of higher plants, including
transport, photosynthesis, hormonal regulation, stress tolerance, and plant-microbe
interactions. (S)
118. Plant Development
(4) Finkelstein
Prerequisites: MCDB 5A-AL, EEMB 5B-BL or MCDB 5B-BL,
MCDB 101A or EEMB 129, or equivalents. Not open for credit to students
who have completed Biology 112 or Botany 111. Lecture, 3 hours; discussion,
1 hour.
Differentiation and morphogenesis of plants: mechanisms
of control by genetic and environmental factors, plant growth regulators,
and cell-cell interactions. (S; not offered 1998-99)
119. Plant Molecular Biology
(3) Christoffersen, Cooper, Finkelstein
Prerequisites: MCDB 108A-B-C or 110, and MCDB 101A-B.
Lecture, 3 hours. Not open to students who have completed Biology 115.
The molecular biology of vascular plants. Emphasis on
the molecular mechanisms by which external and internal factors control
development. Plant-microbe interactions and practical applications of transgenic
plants will also be considered. (F; not offered 1998-99)
120L. Laboratory in Plant Physiology and Development
(3) Cooper, Finkelstein
Prerequisite: MCDB 118 or MCDB 117 (may be taken concurrently).
Not open to students who have completed Botany 112L. Laboratory, 8 hours.
Experiments using classical and molecular approaches
to plant physiology and development. (S; not offered 1998-99)
126A. Basic Pharmacology
(4) Jacobs
Prerequisites: MCDB 101A (may be taken concurrently);
Chemistry 130A-B-C or 107A-B, and 6A-B; or consent of instructor. Same
course as EEMB 126A. Not open for credit to students who have completed
Biology 119A. Lecture, 3 hours; discussion, 1 hour.
Designed to provide the student with a comprehensive
knowledge of the history and scope of pharmacology as a basic science.
Emphasis on the principles of drug action and the relationship of pharmacology
to physiology, chemistry, and biochemistry. (F)
126AL. Pharmacology Lab I
(3) Jacobs
Prerequisite: concurrent enrollment in EEMB 126A.
Not open for credit to students who have completed Biology 119AL. Same
course as EEMB 126AL. Laboratory, 8 hours, discussion, 1 hour.
Analysis of drug sites and mechanisms of action using
isolated tissues, organs, and intact animal preparations. (F)
126AS. Introduction to Molecular Modeling for Pharmacology
(1) Jacobs
Prerequisite: concurrent enrollment in MCDB 126AL
or EEMB 126AL. Same course as EEMB 126AS. Laboratory, 3 hours.
Concepts in molecular modeling and drug-receptor interactions
using 3-D computer graphics.
126B. Basic Pharmacology
(4) Vandenberg
Prerequisites: MCDB 101A or Chemistry 142C; Chemistry
130A-B-C or 107A-B and 108; Chemistry 6A-B. MCDB 108A is strongly recommended.
Not open for credit to students who have completed Biology 119B. Lecture,
3 hours, discussion, 1 hour.
Receptor signaling mechanisms; pharmacology of neurotransmitter
and hormone receptors; molecular and cellular mechanisms of drug-receptor
interactions. (W)
126BL. Pharmacology Laboratory II
(4) Vandenberg
Prerequisite: concurrent enrollment in MCDB 126B.
Not open for credit to students who have completed Biology 119BL. Laboratory,
9 hours, discussion, 1 hour.
An introduction to molecular and biochemical techniques
in pharmacology; drug-receptor binding; receptor isolation; pharmacokinetics;
techniques to evaluate potency, concentration and effects of hormones and
their receptors. (W)
126C. Basic Pharmacology
(4) Wilson
Prerequisite: MCDB 101A or Chemistry 142C; Chemistry
130A-B-C or 107A-B and 108; Chemistry 6A-B. MCDB 108A is strongly recommended.
Not open for credit to students who have completed Biology 119C. Lecture,
3 hours, discussion, 1 hour.
Fundamental principles of pharmacology, drug-receptor
theory, biochemical mechanisms of action of drugs. (S)
131. General Microbiology
(4) Cooper, Ross
Prerequisites; MCDB 5A-AL, EEMB 5B-BL or MCDB 5B-BL;
Chemistry 107A-B and 108 or 130A-B-C. Not open for credit to students who
have completed Biology 104 or 104A. Lecture, 3 hours; discussion, 1 hour.
An introduction to the biological properties of microorganisms;
the historical foundations of the field of microbiology; a study of the
major groups of microorganisms, their structure, physiology, cultivation,
and pathogenicity. (F)
131L. Laboratory in General Microbiology
(2) Cooper
Prerequisite: MCDB 131 (may be taken concurrently).
Not open for credit to students who have completed Biology 104 or 104L.
Laboratory, 6 hours.
Laboratory experiments dealing with the isolation, cultivation,
and physiological, biochemical and genetic analysis of diverse microorganisms.
(F)
132. Bacterial Pathogenesis
(3) Mahan
Prerequisites: MCDB 101A; MCDB 131 recommended. Concurrent
enrollment in MCDB 132L. Not open for credit to students who have completed
Biology 128. Lecture, 3 hours.
The mechanisms by which bacterial pathogens cause disease.
Investigation of the bacterial gene products that are produced during infection
to understand the metabolic, physiological, and genetic factors that contribute
to the virulence of bacterial pathogens. (W)
132L. Bacterial Pathogenesis Laboratory
(3) Mahan
Prerequisite: concurrent enrollment in MCDB 132. Not
open for credit to students who have completed Biology 128L. Laboratory,
6 hours; discussion, 1 hour.
The latest molecular, biochemical, and genetic techniques
available for the identification of microbial gene products that contribute
to infection. Study of the regulatory parameters that govern their expression.
(W)
133. Molecular and Cellular Immunobiology
(5) Sears
Prerequisite: MCDB 101A. Not open for credit to students
who have completed Biology 123. Lecture, 4 hours; discussion, 1 hours.
Introduction to the current concepts of immunology. Emphasis
on immunoglobulin structure and function, cell-cell cooperation in the
immune response, and the role of the major histocompatibility complex and
cytokines in regulating immune responsiveness. (W)
133H. Immunobiology-Honors
(1) Sears
Prerequisite: concurrent enrollment in MCDB 133 or
consent of instructor. Discussion, 2 hours.
Honors component of MCDB 133 focusing on selected aspects
of the immune system and its components using a web browser to run interactive
computer assignments. (W)
133L. Molecular and Cellular Immunobiology Lab
(2) Eardley
Prerequisite: MCDB 133 (may be taken concurrently).
Not open for credit to students who have completed Biology 123L. Laboratory,
6 hours.
Introduction to modern laboratory methods in immunology;
properties and characterization of immunoglobulins and immunoglobulin-secreting
cells; introduction to hybridoma technology; characterization of effector
and regulatory T cells using functional assays. (S)
134. General Animal Virology
(4) Samuel
Prerequisite: MCDB 101A. Not open for credit to students
who have completed Biology 122. Lecture, 3 hours; discussion, 1 hour.
An introduction to the biology of animal viruses with
emphasis on the biochemical and biophysical properties of viruses; the
mechanisms by which animal viruses replicate; the cellular effects of and
response to viral infection; and selected aspects of medical virology.
(S)
134H. General Animal Virology-Honors
(2) Samuel
Prerequisites: concurrent enrollment in MCDB 134 and
consent of instructor. Not open for credit to students who have completed
Biology 122H. Lecture, 1 hour; discussion, 1 hour.
Honors virology course designed to permit an in-depth
consideration of selected aspects of the biology of animal viruses; the
mechanisms by which animal viruses replicate; and the cellular effects
of and response to viral infection. (S)
135. Cellular Growth Control and Oncogenesis
(4) Ballester
Prerequisites: MCDB 101A-B; MCDB 108A-B-C strongly
recommended. Not open for credit to students who have completed Biology
138. Lecture, 3 hours; discussion, 1 hour.
Focus on mechanisms of growth control in eukaryotes.
Topics include: the properties of mammalian cells in culture and how they
relate to malignant cells, growth factors and their receptors, cell cycle
control, oncogenes and tumor suppressor genes. (F)
137. Biology of Fungi
(4) Ross
Prerequisites: MCDB 5A-AL, EEMB 5B-BL or MCDB 5B-BL,
and EEMB 5C-CL, or equivalents, MCDB 101A. Not open for credit to students
who have completed Biology 173. Lecture, 3 hours; laboratory, 3 hours.
Morphology, development, and genetic systems of fungi
and allied protists. The significance of the uniqueness of fungal sexual
and genetic mechanisms and the interactions between fungi and other organisms
will be stressed, with experimental, biotechnology, and medical aspects
emphasized. (S)
139. Medical Microbiology
(3) Eardley
Prerequisites: MCDB 5A-AL, EEMB 5B-BL or MCDB 5B-BL,
and EEMB 5C-CL, or equivalents. Not open for credit to students who have
completed Biology 129. Lecture, 3 hours.
Study of the characteristics of bacteria and viruses,
both pathogenic and adventitious, as they are associated with diseases
of humans. (F)
140L. Recombinant DNA Methods
(4) Smith
Prerequisites: MCDB 101A-B and 110; or 108A-B-C. Not
open for credit to students who have completed Biology 132. Laboratory,
6 hours; tutorial, 6 hours.
Basic techniques in molecular cloning. Screening of recombinant
cDNA libraries, polymerase chain reaction, restriction endonucleases, gel
electrophoresis, DNA sequencing, nucleic acid hybridization. (S)
149. Mariculture for the 21st Century: Research Frontiers
(4) Morse, Chapman, Collins
Prerequisite: upper-division standing. Not open for
credit to students who have completed Biology 149. Same course as EEMB
149. Lecture, 3 hours; discussion, 1 hour.
Recent progress and new directions in research increasing
production of valuable marine animals, plants and microorganisms. Control
of reproduction, development, growth and disease in marine species; problems
encountered in commercializing production; regional and biological solutions;
the role of modern biotechnology. (S)
167. Advanced Topics in Immunobiology
(2) Sears
Prerequisite: MCDB 133 and consent of instructor.
Not open for credit to students who have completed Biology 124. Seminar,
2 hours
Discussion of an advanced topic in immunology during
a weekly two-hour roundtable seminar. Students write and present a critique
of a recent immunological publication. (S)
167H. Immunobiology-Honors
(1) Sears
Prerequisites: concurrent enrollment in MCDB 167 and
consent of instructor.
Honors component of MCDB 167 designed to permit in-depth
consideration of selected aspects of the immune system and its basic constituents.
(S)
182. Introduction to Health Care Delivery
(2) Kohl
Prerequisites: upper-division standing; 3.0 grade-point
average or consent of instructor. Not open for credit to students who have
completed Biology 191. Lecture, 1 hour; laboratory, 3 hours.
Course conducted at UCSB and Santa Barbara Medical Foundation
Clinic involves a series of lectures by UCSB faculty and Clinic physicians
discussing health care delivery. Students also spend three hours per week
"on call" with medical or surgical specialist at Clinic or hospital. (F,W,S)
183. Introduction to Teaching in Biology
(1-5) Staff
Prerequisites: upper-division standing and consent
of instructor. May be repeated for credit to a maximum of 5 units. May
not be applied toward the major.
Students will assist instructor in teaching course in
which the student previously received a grade of A- or better. Activities
will be determined in consultation with the instructor and may include
leading discussion, laboratory, or tutorial section(s), attending lectures
and grading exams.
184. Internship in Biological Sciences
(1-5) Staff
Prerequisites: upper division standing, 2.5 cumulative
grade-point average. Instructor and departmental approval required. May
be repeated for credit to a maximum of 15 units, but no units may be applied
toward the major (except Aquatic Biology. See restrictions in major narrative).
Field, 5-25 hours.
Opportunity to obtain practical biological related research
experience by working under faculty direction as an intern with local,
state, federal, or private agencies. A written report will be submitted
for evaluation.
186. Colloquia in Biomedical Research
(1) Kohl
Prerequisites: MCDB 5A-AL, EEMB 5B-BL or MCDB 5B-BL,
and EEMB 5C-CL, or equivalents. May be repeated for credit in combination
with Biology 195 and BMB 186 to a maximum of 3 units.
Lectures by UCSB faculty from various departments focused
on their current research in a variety of biomedical disciplines.
187. Pharmacology Colloquia
(1) Jacobs, Wilson
Prerequisites: MCDB 5A-AL, EEMB 5B-BL or MCDB 5B-BL,
and EEMB 5C-CL, or equivalents. Same course as EEMB 187. May be repeated
for credit to a maximum of 4 units, but only 2 units may be applied toward
the major. Seminar, 1 hour.
Lectures on active research programs in pharmacology
in the federal, state, and private research sectors. (W,S)
188. Literature in Plant Molecular Biology
(1) Christoffersen, Cooper, Finkelstein
Prerequisite: consent of instructor. Not open for
credit to students who have completed Biology 168. Seminar, 1 hour.
Critical reading and presentation of the current literature
in plant molecular biology, cell biology and development. (F,W,S; not offered
1998-99)
192. Special Topics
(1-4) Staff
Prerequisites: upper-division standing in biology
and consent of instructor or department. May be repeated for credit in
combination with Biology 192 and EEMB 192. Lecture, 1 to 4 hours.
Special topics of current importance in biological sciences.
Course content will vary. Information may be obtained in department office.
194AA-ZZ. Group Studies for Advanced Students
(2) Staff
Prerequisites: upper-division standing and consent
of instructor. May be repeated for credit in combination with Biology 194AA-ZZ
and EEMB 194AA-ZZ to a maximum of 8 units. Individual letter designations
may be repeated for credit to a maximum of 4 units. Seminar, 2 hours.
Oral reports by students.
A-B. Biochemistry-Molecular Biology: Staff
BC. Biochemistry-Molecular Biology: Cooper
DM. Molecular Marine Biology and Marine Biotechnology:
Morse
DS. Molecular and Cellular Immunology: Sears
DV. Developmental Biology: Smith
EO. Genetics: Orias
MP. Microbial Pathogenesis: Mahan
V. Mycology: Ross
X. Cell Biology: Foltz
198. Directed Readings
(1-5) Staff
Prerequisites: a major within MCDB and consent of
instructor and department. Students must (1) have attained upper-division
standing; (2) have a minimum 3.0 grade-point average in upper-division
major courses; (3) have completed at least two upper-division courses in
MCDB or EEMB. Students are limited to 5 units per quarter and 30 units
total in all 98/99/198/199/199RA courses combined. Tutorial, 1-5 hours.
Individual conferences one hour every two weeks. Special
readings designed to broaden the outlook of students and to knit into a
cohesive whole the basic principles underlying the major disciplines in
the field. (F,W,S)
199. Independent Studies
(1-5) Staff
Prerequisites: a major within MCDB and consent of
instructor and department. Students must (1) have attained upper-division
standing; (2) have a minimum 3.0 grade-point average in upper-division
major courses; (3) have completed at least two upper-division courses in
MCDB or EEMB. Students are limited to 5 units per quarter and 30 units
total in all 98/99/198/199/199RA courses combined. Tutorial, 1-3 hours;
field, 1-5 hours.
Hours and credit by arrangement with any faculty member.
Laboratory or field. (F,W,S)
203. Cell Biology
(4) Staff
Prerequisites: MCDB 5A-AL, MCDB 5B-BL or EEMB 5B-BL
or equivalents. Not open for credit to students who have completed Biology
237. Lecture, 3 hours; discussion, 1 hour.
Introduction to the structure and function of cell organelles:
membranes, nucleus, mitochondria, chloroplasts, endoplasmic reticulum,
golgi apparatus, lysosomes, microbodies, microtubules, cilia, centrioles,
and microfilaments. (W)
208AL. Biochemistry Computer Laboratory
(2) Sears
Prerequisite: MCDB 108A (may be taken concurrently).
Mathematics 3A-B or 34A-B strongly recommended.
Computer laboratory analysis of biochemical structures
and the dynamics of their interactions with other molecules. Students will
be required to submit a structural analysis paper on a topic of their
choice. (F)
211. Ciliate Biology
(3) Orias
Prerequisite: consent of instructor. Not open for
credit to students who have completed Biology 211. Lecture, 2 hours; discussion,
1 hour.
Conceptual bases for the experimental use of ciliates
as models of eukaryotic cells in current frontiers of biology: nuclear
differentiation, membrane bioelectrics, cell morphogenesis and hormone
action. An oral presentation of a paper in the recent literature will be
required. (S)
212. Molecular Virology
(5) Samuel
Prerequisites: MCDB 108A-B-C and 101A-B or equivalent,
or consent of instructor. Not open for credit to students who have completed
Biology 212. Lecture, 5 hours.
Consideration of selected animal viruses in terms of
structure, mechanism of genetic expression, and effects of viral gene expression
on cell function, as well as aspects of the virus-host interaction including
viral persistence, interference, and interferon. (S)
214. Neurobiology I
(4) Fisher, Johnson
Prerequisite: MCDB 5A-AL or equivalent. Not open for
credit to students who have completed Biology 208. Lecture, 3 hours; discussion,
1 hour.
Nervous system properties ranging from single cells to
whole organisms, using examples from vertebrates/invertebrates studied
in terms of morphology, physiology, behavior. (F)
215. Developmental Neurobiology: A Molecular and Cellular
Perspective
(4) Staff
Prerequisites: MCDB 5A-AL, MCDB 5B-BL or EEMB 5B-BL,
EEMB 5C-CL; MCDB 101A. MCDB 112 recommended. Not open for credit to students
who have completed Biology 209. Lecture, 3 hours; discussion, 1 hour.
The course begins with fertilization and moves through
sequential stages in the development of the nervous system, including cell
migration and differentiation, axon outgrowth and pathfinding, programmed
cell death, synaptogenesis, learning, memory, neurodegenerative conditions
and current strategies for neuronal regeneration. (S)
216. Molecular and Cellular Neuroscience
(3) Clegg, Feinstein, Fisher, Smith, Vandenberg
Prerequisite: graduate standing or consent of instructor.
Lecture, 2 hours; discussion, 1 hour.
Emphasis on current research investigations into the
development, cell biology, and molecular biology of the nervous system.
Topics will vary based upon current progress in the field. (S)
218A. Nucleic Acids and Proteins
(5) Carbon, Kohlstaedt, Lew, Perona
Prerequisites: graduate standing in biochemistry-molecular
biology, or chemistry, or consent of instructor. Same course as BMB 218A.
Not open for credit to students who have completed Biology 218A. Lecture,
5 hours.
Properties, structure, and structure function analysis
of nucleic acids and proteins; modern methods in nucleic acid research
(synthetic and recombinant DNA, in vitro mutagenesis); protein dynamics
(folding, transport, covalent, and non-covalent structural adaptations
to function). (F)
218B. Molecular and Cellular Biology
(5) Clarke, Clegg, Rothman, Samuel, Wilson
Prerequisite: graduate standing or consent of instructor.
Same course as BMB 218B. Not open for credit to students who have completed
Biology 218B. Lecture, 4 hours; discussion, 1 hour.
The cytoskeleton; chromatin and chromosome organization,
structure, and function; mechanisms of gene expression in prokaryotes and
eukaryotes and their viruses; membrane structure, organization, and protein
trafficking; cell-cell and cell-matrix interactions. (W)
218C. Gene Regulation and Development
(5) Staff
Prerequisite: MCDB 218B or BMB 218B. Same course as
BMB 218C. Not open for credit to students who have completed Biology 218C.
Lecture, 4 hours; Discussion, 1 hour.
Specialized features of plant cells. Regulation of gene
expression during development. Models include prokaryotes (bacteria) and
eukaryotes (plants, yeast, ciliates, C. Elegans, Drosophila, sea urchins,
mouse), with emphasis on systems that undergo cellular differentiation
and cellular rearrangement. (S)
218X. Selected Topics in Gene Regulation and Development
(1-4) Staff
Prerequisite: consent of graduate advisor. Same course
as BMB 218X. Not open for credit to students who have completed Biology
218X. Lecture, 4 hours; discussion 1 hour.
Selected topics in gene regulation and development as
appropriate to fulfill the course requirement of graduate students in biochemistry
and molecular biology. (S)
218Y. Selected Topics in Molecular and Cellular Biology
(1-4) Staff
Prerequisite: consent of graduate advisor. Same course
as BMB 218Y. Not open for credit to students who have completed Biology
218Y. Lecture, 4 hours; discussion 1 hour.
Selected topics in molecular and cellular biology as
appropriate to fulfill the course requirement of graduate students in biochemistry
and molecular biology and molecular, cellular, and developmental biology.
(W)
218Z. Selected Topics in Biochemistry of Nucleic Acids
and Proteins
(1-4) Staff
Prerequisite: consent of graduate advisor. Same course
as BMB 218Z. Not open for credit to students who have completed Biology
218Z. Lecture, 4 hours; discussion, 1 hour.
Selected topics in the biochemistry of nucleic acids
and proteins as appropriate to fulfill the course requirement of graduate
students in biochemistry and molecular biology. (F)
219. Plant Molecular Biology
(3) Christoffersen, Cooper, Finkelstein
Prerequisites: MCDB 108A-B-C and 101A-B, or consent
of the instructor. Not open for credit to students who have completed Biology
215. Lecture, 3 hours.
The molecular biology of vascular plants. Emphasis on
the molecular mechanisms by which external and internal factors control
development. Plant-microbe interactions and practical applications of transgenic
plants will also be considered. (F; not offered 1998-99)
220. Experimental Cytology and Electron Microscopy
(3) Staff
Prerequisites: MCDB 108A-B-C or consent of instructor.
Not open for credit to students who have completed Biology 220. Lecture,
1 hour; laboratory, 6 hours.
An introduction to the techniques of structural cytology.
(S; not offered 1998-99)
221. Preparation and Evaluation of Research Proposals
(1) Foltz
Prerequisites: MCDB 218A-B or BMB 218A-B or consent
of instructor. Lecture, 1 hour.
Instruction in preparation, writing, and evaluation of
research grant proposals. Students are required to submit a full research
proposal (in Federal funding agency format) at the end of the course. (S)
222. Sequence Analysis
(1) Poole
Prerequisite: consent of instructor. Lecture, 1 hour.
Analysis of DNA and protein sequence data. Topics include
protein property prediction, defining sequence similarity, sequence comparison,
and sequence database searching. (F)
226A. Basic Pharmacology
(4) Jacobs
Prerequisite: consent of instructor. Same course as
EEMB 226A. Not open for credit to students who have completed Biology 219A.
Lecture, 3 hours; discussion, 1 hour.
History and scope of pharmacology as a basic science;
principles of drug action and relationship of pharmacology to physiology,
chemistry, biochemistry emphasized. (F)
226AL. Pharmacology Lab I
(4) Jacobs
Prerequisite: concurrent enrollment in EEMB 226A.
Same course as EEMB 226AL Not open for credit to students who have completed
Biology 219AL. Discussion, 1 hour; laboratory, 9 hours.
Analysis of drug sites and mechanisms of action using
isolated tissues, organs, and intact animal preparations. (F)
226AS. Introduction to Molecular Modeling for Pharmacology
(1) Jacobs
Prerequisite: concurrent enrollment in MCDB 226AL
or EEMB 226AL. Same course as EEMB 226AS. Laboratory, 3 hours.
Concepts in molecular modeling and drug-receptor interactions
using 3-D computer graph-
ics. (F)
226B. Basic Pharmacology
(4) Vandenberg
Prerequisite: consent of instructor. Not open for
credit to students who have completed Biology 219B. Lecture, 3 hours; discussion,
1 hour.
Receptor signalling mechanisms; pharmacology of neurotransmitter
and hormone receptors; molecular and cellular mechanisms of drug-receptor
interactions. (W)
226BL. Pharmacology Laboratory II
(4) Vandenberg
Prerequisites: concurrent enrollment in MCDB 226B.
Not open for credit to students who have completed Biology 219BL. Discussion,
1 hour; laboratory, 9 hours.
An Introduction to molecular and biochemical techniques
in pharmacology; drug-receptor binding; receptor isolation; pharmacokinetics;
techniques to evaluate potency, concentration and effects of hormones and
their receptors. (W)
226C. Basic Pharmacology: Principles and Chemotherapy
(4) Wilson
Prerequisite: consent of instructor. Not open for
credit to students who have completed Biology 219C. Lecture, 3 hours; tutorial,
1 hour.
Fundamental principles of pharmacology, drug-receptor
theory, biochemical mechanisms of action of drugs. (S)
227. Cellular and Developmental Biology of Eukaryotic
Microbes (Slime Molds and Fungi)
(3) Ross
Prerequisites: MCDB 101A-B; and MCDB 108A-B-C or 110;
and consent of instructor. Not open for credit to students who have completed
Biology 227. Lecture, 2 hours; discussion, 1 hour.
Current concepts of the molecular basis of cell differentiation
and development in slime molds and fungi. Emphasis on aspects of cell interactions
unique to fungi and the molecular basis of the role of these organisms
in industrial and medical areas. A research paper, written and oral, based
on current literature is required. (W; not offered 1998-99)
231. General Microbiology
(4) Cooper, Ross
Prerequisites: MCDB 5A-AL, MCDB 5B-BL or EEMB 5B-BL;
Chemistry 107A-B and 108, or 130A-B-C. Not open for credit to students
who have completed Biology 207. Lecture, 3 hours; discussion, 1 hour.
Introduction to the biological properties of microorganisms;
historical foundations of the field of microbiology; a study of the major
groups of microorganisms, their structure, physiology, cultivation, and
pathogenicity. (F)
231L. General Microbiology Laboratory
(2) Cooper, Ross
Prerequisite: concurrent enrollment in MCDB 231. Laboratory,
6 hours.
Laboratory experiments on the isolation, cultivation,
and analysis of diverse microorganisms.
232. Bacterial Pathogenesis
(3) Mahan
Prerequisite: MCDB 101A-B. MCDB 231 recommended. Not
open for credit to students who have completed Biology 228. Lecture, 3
hours.
The mechanisms by which bacterial pathogens cause disease.
Investigation of the bacterial gene products produced during infection
to understand the metabolic, physiological, and genetic factors that contribute
to the virulence of bacterial
pathogens. (W)
232L. Bacterial Pathogenesis Laboratory
(3) Mahan
Prerequisite: MCDB 232 (may be taken concurrently).
Not open for credit to students who have completed Biology 228L. Laboratory,
6 hours; discussion, 1 hour.
The latest molecular, biochemical, and genetic techniques
available for the identification of microbial gene products that contribute
to infection. Study of the regulatory parameters that govern their expression.
(W)
233. Molecular and Cellular Immunobiology
(3) Sears
Prerequisites: MCDB 101A-B, 108A-B-C or equivalent,
or consent of instructor. Not open for credit to students who have completed
Biology 223. Lecture, 3 hours.
Introduction to, and evaluation of, the current concepts
of immunology. Emphasis on immunoglobulin structure and function, cell-cell
cooperation in the immune response, and the role of the major histocompatibility
complex in regulating immune responsiveness. (W)
237. Biology of Fungi
(4) Ross
Prerequisites: MCDB 5A-AL, MCDB 5B-BL or EEMB 5B-BL,
EEMB 5C-CL or equivalents; MCDB 101A (may be taken concurrently) or consent
of instructor. Not open for credit to students who have completed Biology
273. Lecture 3 hours; laboratory, 3 hours.
Morphology, development, and genetic systems of fungi
and allied protists. The significance of the uniqueness of fungal sexual
and genetic mechanisms and the interactions between fungi and other organisms
will be stressed, with experimental, biotechnology, and medical aspects
emphasized. (S)
249. Mariculture: Research Frontiers in Farming the
Sea
(4) Morse, Chapman, Collins
Prerequisite: graduate standing. Same course as EEMB
249. Not open for credit to students who have completed Biology 249. Lecture,
3 hours; discussion, 1 hour.
Recent progress and new directions in research increasing
production of valuable marine animals, plants and microorganisms. Control
of reproduction, development, growth and disease in marine species; problems
encountered in commercializing production; regional and biological solutions;
the role of modern biotechnology. (S)
260. Research Seminar in Biochemistry-Molecular Biology
(1) Cooper, Poole
Prerequisite: graduate standing. Same course as BMB
260. Not open for credit to students who have completed Biology 260. Seminar,
1 hour.
Seminars on research in progress presented by faculty
of the Department of Chemistry and Department of Molecular, Cellular and
Developmental Biology. (F,W,S)
261. Literature in Immunology
(1) Sears
Prerequisite: consent of instructor. Not open for
credit to students who have completed Biology 261. Seminar, 1 hour.
Critical reading and presentation of recent literature
in immunology. (F,W,S)
262. Research Progress in Molecular, Cellular and Developmental
Biology
(1) Cooper
Same course as BMB 262. Not open for credit to students
who have completed Biology 262. Seminar, 1 hour.
Research presentations by postdoctoral fellows and advanced
Ph.D. students of research progress in the department. (F,W,S)
263. Progress in Biochemistry and Molecular Biology
(1) Staff
Same course as BMB 263. Not open for credit to students
who have completed Biology 263. Seminar, 1 hour.
Research seminars presented by invited speakers on current
research topics. (F,W,S)
264. Literature in Nucleic Acids and Chromosomes
(1) Carbon, Clarke
Prerequisite: graduate standing. Not open for credit
to students who have completed Biology 264. Seminar, 1 hour.
Critical reading and presentation of the recent literature
on nucleic acids and chromosomes by staff, postdoctoral fellows, and graduate
students. (F,W,S)
265. Literature in Virology
(1) Samuel
Prerequisites: graduate standing and consent of instructor.
Not open for credit to students who have completed Biology 265. Seminar,
1 hour.
Critical reading and presentation of the recent literature
on animal viruses and host cells by graduate students, postdoctoral fellows,
and staff. (F,W,S)
266. Literature in Neurobiology
(1) Fisher, Poole, Clegg, Feinstein, Vandenberg
Prerequisite: consent of instructor. Not open for
credit to students who have completed Biology 266. Seminar, 1 hour.
Critical reading and presentation of the literature in
modern neurobiology. (F,W)
267. Advanced Topics in Immunobiology
(2) Sears
Prerequisite: MCDB 233 (may be taken concurrently)
or consent of instructor. Not open for credit to students who have completed
Biology 224. Lecture, 2 hours.
Contemporary developments and controversies regarding
the biology of the immune system.
268. Literature in Plant Molecular Biology
(1) Christoffersen
Prerequisite: graduate standing. Not open for credit
to students who have completed Biology 268. Seminar, 1 hour.
Critical reading and presentation of the current literature
in higher plant molecular biology, cell biology, and development. (F,W,S)
269. Literature in Pharmacology
(1) Jacobs, Wilson
Prerequisite: graduate standing in biological sciences.
Same course as EEMB 269. Not open for credit to students who have completed
Biology 269. Seminar, 1 hour.
Critical reading and presentation of current literature
in topics on pharmacology. (F,W,S)
290AA-ZZ. Group Studies
(2) Staff
Prerequisite: consent of instructor.
Presentation and discussion of current research, to be
selected from the following list.
A. Research in Molecular Marine Biology: Morse
B. Research in Biomineralization: Morse
C. Studies in Regulation of Cell Proliferation: Ballester
CC. Centromeres and Chromosomes-Models and Analysis:
Carbon
CS. Advanced Topics in Chromosome Segregation: Clarke
DN. Developmental Neurobiology: Clegg
LW. Microtubule Dynamics and Functions: Wilson
MM. Bacterial Pathogenesis: Mahan
PM. Molecular Plant-Microbe Interactions: Cooper
RF. Plant Developmental Genetics: Finkelstein
S. Molecular Virology and Interferon Action: Samuel
SK. Research in Retinal Cell Biology: Fisher
V. Current Research on Cell and Developmental Biology
of Fungi: Ross
VA. Molecular Neurobiology-Ion Channels: Vandenberg
292. Advanced Special Topics in Biological Sciences
(1-4) Staff
Prerequisites: graduate standing and consent of instructor.
May be repeated for credit in combination with Biology 292. Lecture, 1-4
hours.
Special topics of current importance in biological sciences.
Course content will vary. Information on course content may be obtained
in the department office.
500. Teaching Assistant Orientation
(1) Staff
Required of all teaching assistants. No unit credit
allowed toward advanced degree. May be repeated for credit in combination
with Biology 500. Workshop, 1 hour.
General orientation regarding the University of California
and the Santa Barbara campus; various pertinent regulations, officials
and their functions, staff and functions; services available to teaching
assistants and to students. Prospective teaching assistants are encouraged
to take this course during the fall quarter prior to their employment.
(F)
501. Practicum in Instruction
(1-4) Staff
Prerequisite: concurrent teaching assistant employment.
No unit credit allowed toward advanced degree. May be repeated for credit
in combination with Biology 501. Workshop, 3-12 hours.
Practical experience in teaching within specified areas
of biology. Students will have responsibility for one or more laboratory
and/or discussion sections. Staff will periodically observe teaching assistants
in actual teaching situations. Evaluation forms will be completed by members
of the class sections. (F,W,S)
502. Techniques of Teaching and Laboratory Class Supervision
(1-2) Staff
Prerequisite: concurrent teaching assistant employment.
Required of all teaching assistants. No unit credit allowed toward advanced
degree. May be repeated for credit in combination with Biology 502. Discussion,
1 hour.
Weekly discussion and readings on techniques of teaching
including lecturing, leading discussions, writing and grading exams, student-teacher
interactions, classroom dynamics, and teaching philosophy. (F,W)
503. Research Practicum in Biology
(1-2) Staff
May be repeated for credit in combination with Biology
503. Tutorial, 1-2 hours.
Basic procedures and methods of research in a specified
area as determined by consultation between the supervising faculty member
and the research assistant. Includes weekly meetings and consultations,
and formal evaluations. (F,W,S)
595AA-ZZ. Group Studies
(2) Staff
Prerequisite: consent of instructor. May be repeated
for credit in combination with Biology 595AA-ZZ and EEMB 595AA-ZZ to a
maximum of 8 units. Individual letter designations may be repeated for
credit to a maximum of 4 units. Seminar, 2 hours.
A critical review of research in selected fields of biology.
Subject matter for these seminars will be selected from the following list:
A-B. Biochemistry-Molecular Biology: Staff
BC. Biochemistry/Molecular Biology: Cooper
DM. Molecular Marine Biology and Marine Biotechnology:
Morse
DS. Molecular and Cellular Immunology: Sears
DV. Developmental Biology: Smith
EO. Genetics: Orias
F. General Physiology: Staff
G. Virology: Samuel
MM. Contemporary Topics in Biochemistry and Molecular
Biology: Sears
MP. Microbial Pathogenesis: Mahan
NN. Literature in Eukaryotic Molecular Genetics: Orias
V. Mycology: Ross
X. Cell Biology: Foltz
596. Directed Reading and Research
(2-12) Staff
Prerequisites: consent of instructor.
Hours and credit by arrangement with faculty.
597. Individual Study for Master's Comprehensive Examinations
and Ph.D. Examinations
(1-12) Staff
Prerequisites: consent of instructor. May be repeated
for credit in combination with Biology 597. No unit credit allowed toward
advanced degree. Students are limited to 24 units per examination, and
12 units per quarter.
Individual study for M.A. comprehensive examinations
and Ph.D. examinations.
598. Master's Thesis Research and Preparation
(1-12) Staff
Prerequisites: M.A. (thesis) candidate and consent
of committee chair. May be repeated for credit in combination with Biology
598 to a maximum of 12 units. No unit credit allowed toward advanced degree.
For research underlying the thesis and writing of the
thesis.
599. Ph.D. Dissertation Preparation
(1-12) Staff
Prerequisites: Ph.D. candidate and consent of instructor.
May be repeated for credit in combination with Biology 599 to a maximum
of 12 units.
For writing of the dissertation.